R985 - Vp - Toxicology SciencesPubblicato il 30-10-2022 - Evotec Wd in Verona
Evotec is a leader in the discovery and development of novel drugs with operational sites in Europe and the US. The Company has built substantial drug discovery and development expertise and amultimodality platform that comprises a unique combination of innovative technologies, data and science for the discovery, development, and production of first-in-class and best-in-class pharmaceutical products. Evotec leverages this “Data-driven R&D; Autobahn to Cures” for proprietary projects and within a network of partners including all Top 20 Pharma and over 800 biotechnology companies, academic institutions, as well as other healthcare stakeholders. Evotec has strategic activities in a broad range of currently underserved therapeutic areas,
including e.g. neurology, oncology, as well as metabolic and infectious diseases.
Evotec has evolved into one of the global leaders in providing complete drug discovery and development solutions on a stand-alone basis or through holistic, fully integrated solutions. As part of the Evotec integrated R&D; continuum, the Global Drug Development Business Unit (GDD) provides API and Drug Product Development and Manufacturing, Preclinical and IND enabling GLP/GMP programs as well as Clinical Development and Regulatory Affairs.
The Preclinical Development business unit (PCD) is part of GDD and has a pivotal role in the identification and elucidation of potential safety issues of novel compounds as early as possible, and in designing and performing the regulated studies required by the authorities to support IND applications. PCD includes all the critical actors necessary to support these studies, including Safety Assessment, LAS, Regulated Bioanalysis and Biomarkers, ADME, Pathology.
GDD interacts also with the Integrated Drug Discovery Business Units (IDD) to support seamless and successful transition of drug candidates to preclinical and clinical development phases. Discovery and development of drug besides the small molecules, is increasingly oriented to molecule of biotechnological origin with a significant diversification of the drug candidate portfolio. In this evolving situation, Scientific and Quality Excellence of GDD must be achieved also in the new modalities Evotec is entering.
The Preclinical Development organization is characterised by an elevated standard in operational management with tactic and strategic decisions always backed up by data and fit for purpose metrics and Key Performance Indexes.
We are looking for a seasoned and highly motivated professionalwho will help us in consolidating theScientific Excellence in toxicology and build the strategy for preclinical development.
The role and responsibilities
The VP, Toxicology Sciences will report directly into the Head of Global Preclinical Development and will be part a qualified team within the Preclinical Development business unit.
Promote and consolidate the scientific excellence in toxicology
Actively contribute to the definition to the scientific and commercial strategy of Preclinical Development in close collaboration with the Head of PCD and the PCD Leadership Team.
Support Innovation strategies and stimulate the creation of new ideas within the Preclinical Development Business Line.
Advise/elaborate on safety assessment strategies in accordance with the need of the customers especially within the framework of the integrated development programs.
Provide expert data-driven consultancy to integrated projects combining multidisciplinary information.
Provide expert input on gap analysis for development of novel therapies
Provide expert technical and scientific appraisal of safety data in due diligences.
Provide strong and influential scientific leadership in toxicology to PCD and Evotec as needed.
Assess Evotec safety platforms and make potential recommendations for investments that will improve human safety predictions
Lead and manage the Toxicology sciences (TTM) unit
Provide coaching, scientific direction and guidance to the team.
Support the team to provide clear directions and indications on the safety assessment strategy.
Support the successful delivery of Development proposals especially as part of an integrated project and in accordance with customer expectations.
Promote and nurture strong collaboration with other scientists within PCD and IDD
Work in collaboration with other discipline experts to contribute to the successful delivery of projects.
Maintain collaborative relationships with internal and external clients to ensure clients’ satisfaction.
Collaborate with clients, consultants, Study Directors, Regulatory Affairs and regulatory officials regarding studies, protocols, procedures, inspections, etc
Collaborate with clients and the Discovery Safety Leader regarding the integrated R&D; projects’ strategy on safety assessment
Contribute to the consolidation of research to development continuum for safety assessment
Consult on best practices/harmonisation process
The requirements for the role
Excellent knowledge & expertise in safety assessment in pharmaceutical R&D;, particularly in the drug development process and associated scientific and regulatory elements with at least 10 years of experience.
Expertise in ADME in the context of safety assessment is a plus.
Experience in the Contract Research Services business is a plus.
Deep understanding of the drug development process
Experience working in multidisciplinary teams
Demonstrated successful leadership, planning, can-do attitude and excellent organizational skills.
Demonstrated ability to work in a matrix environment.
Strong customer focus, through active listening so connecting the customer needs to Evotec’s solutions. Strong sense of accountability for the outcome.
Flexible and adaptable with an open minded view and creative problem solving skills.
Experience managing team performance and team development and scientific growth
Excellent written and oral communication. Capable to communicate effectively in English.
Exceptional team working attitude