Postdoctoral Researcher In Neuro Epigenetics
Pubblicato il 01-08-2026 - Embl in Italia
Position Overview We are looking for a curious, creative, and driven Postdoctoral Researcher to join the research group of Mathieu Boulard at EMBL Rome to study gene regulation in neurons.
Our research focuses on how chromatin governs olfactory receptor gene choice, an epigenetic mechanism by which olfactory neurons express a single olfactory receptor gene while repressing hundreds of unselected paralogous genes. We use mouse genetics, molecular biology, flow cytometry, microscopy, epigenomic and transcriptomic profiling, and computational genomics. A recent achievement is the discovery of the first factor that enforces the monogenetic transcription of olfactory receptor genes (Tabaro et al.).
The lab is located in the Epigenetics and Neurobiology Unit at EMBL Rome, 30 minutes north of Rome, Italy, offering state‑of‑the‑art core facilities and a highly dynamic, inclusive, multicultural environment.
Responsibilities You will play a central role in exploring the molecular logic of allelic exclusion using the paradigm of olfactory receptor gene choice,
with a central goal of profiling chromatin and transcription in subpopulations of olfactory sensory neurons. You will work closely with other lab members and contribute to team efforts on related aspects.
Qualifications
- A PhD in a life science discipline.
- A strong interest in functional genome biology and/or molecular neuroscience.
- Expertise in one of the following is essential: chromatin biology and/or mouse genetics.
- Hands‑on in vivo experience with mouse models or another model organism.
- Experience with transcriptomics and epigenomic profiling (RNA‑seq, Cut&run;).
- Ability to work independently while contributing to a collaborative team.
- Excellent communication and interpersonal skills with the highest ethical standards.
Additional desirable experience:
- Experience with cell sorting using flow cytometry.
- Knowledge of Italian is not required.
Benefits & Compensation Starting date: Before September 1, 2