Guselkumab For The Treatment Of Psoriatic Arthritis Effectiveness Results By Ultrasound
Pubblicato il 10-08-2026 - DecenTrialz in Bari
Actively Recruiting
Age: 18Years +
All Genders
ID07220824
Guselkumab for the Treatment of Psoriatic Arthritis Effectiveness Results by Ultrasound
Led by Janssen Research & Development, LLC
Updated on 2026-06-05
200
Participants Needed
21
Research Sites
8 weeks
Total Duration
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What This Trial Is About
Researchers are evaluating how well guselkumab works to improve symptoms of psoriatic arthritis, an inflammatory joint disease affecting people with psoriasis, which causes red, scaly skin patches. This observational study uses musculoskeletal ultrasound MSUS to assess treatment effects in a real-world setting, focusing on participants with active psoriatic arthritis who are treated with guselkumab as part of standard care.
Participants with confirmed psoriatic arthritis treated with guselkumab according to usual clinical practice will be included. No study drugs are provided instead, data collected during routine care, including ultrasound exam results, will be gathered. Participants will also be asked questions about their health and well-being as part of the study. During the study, researchers will measure changes in joint inflammation using ultrasound and assess disease activity and pain at several time points, including weeks 12, 24, and 52. They will track improvement in enthesitis, persistence with guselkumab treatment, physical function, and any adverse events. The study duration allows monitoring up to 52 weeks, with assessments based on clinical and imaging data obtained during routine visits.
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Brief Title
A Study of Guselkumab in Participants With Psoriatic Arthritis (PsA) in a Real-World Setting
Who Can Participate
Age: 18Years +
All Genders
Eligibility Criteria
You may qualify if you...
Diagnosis of psoriatic arth