Alfasigma is a privately held global healthcare company founded over 75 years ago in Italy, where it remains headquartered today in Bologna and Milan. The Group operates in over 100 markets spanning Europe, North and South America, Asia, and Africa. Over three years ago, we embarked on a transformative journey to become a truly global innovative healthcare company with a leading focus on Gastrointestinal (GI) health . We have experienced remarkable growth, nearly doubled our revenues, expanding geographically, and integrating several key acquisitions. We have also evolved our portfolio, expanded into rare and specialty segments, and strengthened our pipeline and people's capabilities.
But our journey is far from complete In fact, this is just the beginning of a bold new chapter in Alfasigma's history. We are committed to advancing innovation and leveraging our deep expertise to provide better health and a better quality of life for patients and consumers worldwide and expand our reach across diverse markets.
Position Summary

This role is responsible for supporting the characterization of the clinical pharmacology profile of compounds within the Alfasigma pipeline. The Sr. Manager, Global Clinical Pharmacology serves as a key representative in cross-functional program and study teams, contributing to the development of clinical pharmacology strategies and overseeing the execution of studies and analyses through external CROs.
The role includes contribution to regulatory documentation, presentation of PK/PD data to internal stakeholders, and involvement in scientific publications. The individual also manages outsourced pharmacometric activities, including the development and implementation of PK/PD and disease models to support data‐driven decision‐making and evaluate vantaggi‐risk profiles.
Principal Accountabilities
Lead the design and execution of Phase 1 clinical pharmacology studies (e.g., SAD, MAD, bioavailability, organ impairment, drug‐drug interaction), includ

Sr. Manager, Global Clinical Pharmacology

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