Postdoc Calviello Lab
Pubblicato il 15-08-2026 - Altro in Roma
Build the science that shapes the future of human health.
Application closing date:
Human Technopole (Milan) is a rapidly expanding life science institute where international researchers and cutting-edge technologies converge to accelerate biomedical discovery. Our mission is to transform bold scientific ideas into advances that improve human health.
About the role:
The position will be a joint appointment between the Functional Genomics and the Molecular Cell Biology Research Centres, and jointly supervised by Dr. Lorenzo Calviello and Dr. Gaia Pigino. The position is financially supported by the Human Technopole Ciliopathies Flagship Research Programme ,a multidisciplinary initiative that brings together several Research Groups to dissect the molecular mechanisms underlying ciliary function at multiple scales. Our overarching goal is to achieve a mechanistic understanding of ciliopathies, a diverse group of human disorders characterized by heterogeneous clinical manifestations that ultimately arise from dysfunction of the ciliary organelle.
The successful candidate will be work in a world-class environment with international leaders in mRNA biology, Structural Biology, Cell Biology, advanced analytics and cutting-edge -omics technologies, and apply state-of-the art methods in transcriptomics, biochemistry, fluorescence and cryo-electron tomography to illuminate the biology of RNA and protein synthesis in subcellular space.
This project investigates how RNA localization and compartment-specific translation contribute to the assembly and maintenance of the primary cilium, addressing a largely unexplored layer of organelle regulation. By integrating subcellular transcriptomics, selective ribosome profiling, proteomics, and structural approaches, we aim to define the ciliary transcriptome, identify localized translation events, and characterize ribonucleoprotein complexes that drive ciliogenesis.
Collaborations and interactions with all the involved Research Groups ar