Principal Research Scientist

15 ago - Pomezia
Instruct-Eric

Pomezia, Italy

Application deadline: 31 Aug 2026

We are seeking a talented, highly motivated Crystallographer with a strong passion for structural biology and structure-based drug discovery. The successful candidate will join a rapidly expanding Protein Production and NMR team and contribute to a collaborative, multidisciplinary research environment focused on advancing drug discovery projects involving proteins, nucleic acids, peptides, and small-molecule ligands. The ideal candidate will have a solid background in macromolecular crystallography and a demonstrated track record of delivering high-quality scientific results. She/He should possess extensive training in structural biology, strong analytical and problem-solving skills, and a creative, innovative approach to addressing complex scientific challenges. A commitment to continuous learning and scientific excellence is essential. The role requires hands-on expertise in protein crystallization, diffraction data collection, structure determination, and structural analysis.



The successful applicant will work closely with scientists across multiple disciplines to generate high-impact structural insights that guide drug discovery and biomolecular research programs.

Key Responsibilities

Lead and execute crystal structure determination projects using X-ray crystallography, electron diffraction, and complementary structural biology techniques
Independently analyze, interpret, integrate and communicate experimental data and structural insights to internal project teams, external collaborators, and clients
Design, develop, and optimize experimental strategies to address challenging crystallographic and structure determination problems
Maintain accurate experimental records and contribute to laboratory operations, including reagent procurement, inventory management, and equipment oversight
Provide scientific leadership and intellectual input to structure-based drug discovery programs, working closely with multidiscip

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