Principal Research Scientist

18 ago - Pomezia
Instruct-Eric

Pomezia, Italy

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Application deadline: 31 Aug 2026

We are seeking a talented, highly motivated Crystallographer with a strong passion for structural biology and structure-based drug discovery. The successful candidate will join a rapidly expanding Protein Production and NMR team and contribute to a collaborative, multidisciplinary research environment focused on advancing drug discovery projects involving proteins, nucleic acids, peptides, and small-molecule ligands. The ideal candidate will have a solid background in macromolecular crystallography and a demonstrated track record of delivering high-quality scientific results. She/He should possess extensive training in structural biology, strong analytical and problem-solving skills, and a creative, innovative approach to addressing complex scientific challenges. A commitment to continuous learning and scientific excellence is essential. The role requires hands-on expertise in protein crystallization,



diffraction data collection, structure determination, and structural analysis. The successful applicant will work closely with scientists across multiple disciplines to generate high-impact structural insights that guide drug discovery and biomolecular research programs.

Key Responsibilities

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- Lead and execute crystal structure determination projects using X-ray crystallography, electron diffraction, and complementary structural biology techniques
- Independently analyze, interpret, integrate and communicate experimental data and structural insights to internal project teams, external collaborators, and clients
- Design, develop, and optimize experimental strategies to address challenging crystallographic and structure determination problems
- Maintain accurate experimental records and contribute to laboratory operations, including reagent procurement, inventory management, and equipment overs

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