Researcher - BRIDGE project

Vedi l’offerta su Go Lavoro: golavoro.it/annuncio-lavoro/7gzuyx

The Laimburg Research Centre is the leading research institute for agriculture and food quality in South Tyrol (Italy). We operate mainly in applied research with the aim of increasing the competitiveness and sustainability of South Tyrolean agriculture and of ensuring the quality of agricultural products.

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For the research project BRIDGE “Exploring Bioactivity of Natural Compounds: From Encapsulation Strategies to Drug Discovery for Biomedical Targets", funded by Research Südtirol (call 2024), CUP H33C26000290005, the working group “Laboratory of NMR Spectroscopy” at Laimburg Research Centre is looking for:
Researcher - Code BR.26-NMR-02.22
The project aims to identify, characterize, and optimize bioactive compounds derived from apple and grape by-products, as well as elucidate their molecular mechanisms of action against protein aggregation associated with neurodegenerative diseases.
Your Responsibilities

Expression, purification,



and characterization of recombinant amyloidogenic proteins
Development and application of NMR methods to study protein aggregation and protein–ligand interactions
Screening of natural extracts, purified compounds, and encapsulated formulations as aggregation inhibitors using NMR spectroscopy and LC-MS
Investigation of the molecular mechanisms underlying inhibition of amyloid formation
Analysis of aggregation kinetics and biophysical data
Preparation of scientific reports, publications, and presentations
Collaboration with project partners in natural product chemistry, encapsulation technologies, and computational drug discovery

Your Profile

Completed university studies of at least three years attested by a diploma in chemistry, biotechnology, natural sciences or similar
Good knowledge of Italian or German (C1 level) language - to be evaluated during the interview
Good knowledge of English (B2

Vedi l’offerta su Go Lavoro: golavoro.it/annuncio-lavoro/7gzuyx