20 ago - Milano
Human Technopole
**APPLICATION CLOSING DATE: May 29th, 2025** HT is an interdisciplinary research institute, created and supported by the Italian government, whose aim is to develop innovative strategies to promote human health through a multidisciplinary and integrated approach, combining genomics, computational and structural biology and neuroscience, as well as data and decision sciences. Human Technopole is looking for a **Postdoc**in Soskic Research Group part of the Genomics Research Centre. Soskic Group studies molecular mechanisms that regulate B cell activation, antibody production and their genetic variability. We use a wide range of immunological and genomic assays to study B cell biology, antibody diversity and variation in the human immune system in health and disease. **Your main tasks and responsibilities**: - Leverage advanced methodologies to integrate imaging with genomics data to dissect molecular mechanisms regulating B cell fate choice;
- Develop new ideas to investigate B cell differentiation and study antibody diversification;
- Managing data analysis within their project;
- Generating reliable data for publication in the projects to which they are assigned and recording all data and results in specified forms (paper and electronic);
- Publishing reproducible research;
- Interacting and supporting other group members whenever needed;
- Sharing and discussing research results with collaborators. **Mandatory requirements**: - PhD in immunology, cell biology or equivalent (or PhD is going to be awarded in the next 6 months);
- Experience with basic imaging techniques (for example confocal microscopy or similar);
- Experience with immune cell culture;
- Fluency in English - HT is an international research institute and English will be the main language spoken in the lab. **Preferred requirements**: - Experience with B cell isolation, manipulation, activation and culture;
- Experience in flow cytometry;
- Experience with advanced imaging techniques such as super-resolution;
- Experience with genomic technologies (e.g. scRNA-seq);
- Experience in molecular biology (e.g. CRISPR/Cas9 genome editing). **Organisational and personal skills**: - Strong interpersonal skills demonstrated by the ability to lead and gain the assistance and cooperation of others in a team endeavor;
- Ability to manage competing priorities in a fast-paced environment and to work independently;
- Ability to build trust through operating with transparency and creating an open and positive environment;
- Ability to work in a multi-cultural, multi-ethnic environment with sensitivity and respect for diversity; **Application Instructions**: - A full CV in English
- Name and contact details of at least 2 referees **WHY HUMAN TECHNOPOLE?**
- Our working environment is international, friendly and inclusive. We work together across disciplines leveraging synergies between their diverse skill sets and methodological approaches.
- We believe that highly diverse teams yield the best and most innovative results. **Main benefits**
- Welfare plans
- Canteen service
- Work-life balance provisions
- Italian language training for foreigners
- Parental leave up to 1 year and other support for new parents
- Counseling **Number of positions offered**: 1 **Contract offered**: CCNL Chimico Farmaceutico, fixed term 4 years - Employee level **Salary indication**: € 40k **The position is based in Milan
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