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Principal Pharmacometrician - Remote

Pubblicato il 28-08-2026 - Thermo Fisher Scientific in Milano

**Work Schedule** Other **Environmental Conditions** Office At Thermo Fisher Scientific, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life - enabling our customers to make the world healthier, cleaner and safer. We provide our teams with the resources needed to achieve individual career goals while taking science a step beyond through research, development and delivery of life-changing therapies. With clinical trials conducted in 100+ countries and ongoing development of novel frameworks for clinical research through our PPD clinical research portfolio, our work spans laboratory, digital and decentralized clinical trial services. Your determination to deliver quality and accuracy will improve health outcomes that people and communities depend on - now and in the future. **Location/Division Specific Information**:
**Discover Impactful Work**:
The Principal Pharmacometrician role is responsible for overseeing the design, analysis, interpretation and implementation of modelling and simulation within the clinical pharmacology team. **Keys to Success**:
**Education**: - Ph.D. or PharmD. in relevant discipline (mathematics, statistics, pharmacokinetics, pharmaceutical sciences, bioengineering, etc), with an emphasis on clinical pharmacokinetics **Experience**: - 5+ years in the Pharmaceutical or CRO Industry
- Must have experience with pharmacokinetic, medical, pharmaceutical and research concepts




- Experience required in pharmacokinetic analysis and modeling with strong theoretical background; should have a proven record of accomplishments and publications **Knowledge, Skills, Abilities**: - ** Must have experience and be proficient as a pharmacokinetic modeler using R and NONMEM software** (familiarity with other modelling packages would be advantageous: Phoenix NLME, Simcyp, Gastroplus, Monolix, etc)
- Strong quantitative skills to develop models with nonlinear behavior, mechanistic or semi-mechanistic components, **including must have dose-response modeling experience**, QTc analysis, CAR-T analysis, etc.
- Competent in pharmacokinetic/pharmacodynamic theory
- Excellent communication skills, both written and oral
- Ability to guide and manage multiple projects, delivering within required timelines.
- Self-starter, able to initiate work and motivate others
- Ability to keep others informed of progress
- Excellent problem solving capabilities and organizational skills
- Ability and desire to support, mentor and train others within the team
- Must have experience creating NONMEM dataset specifications using SDTM and ADaM datasets
- Strong quantitative skills to develop models with nonlinear behavior, mechanistic or semi-mechanistic components, including must have dose-response modeling experience **Benefits**:
We offer competitive remuneration, annual incentive plan premio, healthcare, and a range of employee benefits. Thermo Fisher Scientific offers employment with an innovative, forward-thinking organization, and outstanding career and development prospects. We offer an exciting company culture that stands for integrity, intensity, involvement, and innovation!

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