11 set - Roma
San Raffaele Telethon Institute for Gene Therapy (SR-Tiget)
SR-Tiget was created in 1996 as a joint-venture between Fondazione Telethon and Ospedale San Raffaele (OSR), with the mission to perform cutting edge research on gene and cell therapy and to translate its results into therapeutic advances for genetic diseases. The Institute is located within the OSR campus, which includes a large multi-disciplinary research hospital, a biomedical research center, a university and also hosts several biotechnologies companies. Over the years, SR-Tiget has given a pioneering contribution to the gene and cell therapy field with relevant discoveries in vector design, gene transfer and gene editing strategies, stem cell biology, identity and mechanism of action of regulatory cells in immune responses and innate immune cells in cancer.
SR-Tiget has also established the resources and framework for translating these advances into novel experimental therapies and has implemented several successful gene therapy clinical trials, which have already treated >
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150 patients and led to the filing and approval of 3 novel advanced therapy medicines.
We are looking for a motivated Lab Technician/Research Assistant to work in projects focused on the development of innovative Advanced Therapy Medicinal Products (ATMP) based on genetically engineered T lymphocytes and hematopoietic stem cells (HSC).
Main tasks
Cell culture and genetic modification (lentiviral vector transduction, gene editing)
Process scale-up and standardization
Cell-based assays, molecular assays, flow cytometry analyses
Preparation of standard lab procedures and protocols
General lab support
Qualifications and skills
Master Degree (Biology, Biotechnology or equivalent)
Strong wet lab experience
Experience in ATMP and/or Good Manufacturing Practices as a plus
High accuracy, reliability, precision
Friendly, collaborative, proactive mindset
Good oral and written English
We offer
Fixed term employment, 1 year, Fondazione Telethon ETS research contract, gross annual salary 25. € depending on qualifications and experience A dynamic environment and the chance to give important contribution to clinical translation of innovative ATMP
Applications should include CV with name and contact details of at least one referee. xkiyazw Evaluation of applications/interviews will begin immediately and continue until the position is filled.
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