Pica Code-055 RATIONAL DESIGN OF MULTI-TARGET K-RAS AND AINHIBITORS AS POTENTIAL ANTI

27 set - Roma
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Organisation/Company UNIMORE Research Field Chemistry » Applied chemistry Researcher Profile Recognised Researcher (R2) Leading Researcher (R4) First Stage Researcher (R1) Established Researcher (R3) Application Deadline 8 Oct 2026 - 13:00 (UTC) Country Italy Type of Contract To be defined Job Status Not Applicable Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description
The research activity will consist in the design and development of dual inhibitors of
the ADAM17 and K-RasG12C proteins as potential anti-tumour agents, by using
structure-based in silico methods. An evaluation of the structure-activity




relationships on the targets of interest will also be carried out of the developed
compounds. The final goal of this activity is the identification of molecules with high
efficacy and selectivity, potentially applicable to the treatment of non-small cell lung
cancer.

Italy

Eligibility of fellows: country/ies of residence:

OTHER

Eligibility of fellows: nationality/ies:

OTHER

Selection process

selective public procedure by qualifications and interview

Contact phone: (phone hidden)-6447-6450-6072

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