Director, safety physician

04 ott - Italia
Singular: Building Brilliant Biotechs

Safety Physician – Director Level Global Development | Rare Disease & Neurology | UK You are a medically trained safety leader who wants to move beyond execution and play a defining role in how development programmes are designed, challenged and advanced. We are partnering with a European headquartered, science‐driven biopharmaceutical company with a growing global development portfolio.
As the organisation expands its pipeline, it is bringing more strategic safety leadership in‐house to support complex, non‐oncology programmes in rare disease and neurology. This is a Director‐level role with full ownership of multiple assets across development. You will not be a purely operational pharmacovigilance lead; instead, you will act as the safety thought‐partner to clinical, regulatory, biostatistics and governance teams, shaping risk–benefit strategy from early development through Phase III.
What You Will Do
You will own the global safety strategy for multiple development programmes, giving you real authority to influence how assets are designed, assessed and advanced.



Rather than reacting late, you will shape safety thinking early, improving study quality, reducing regulatory friction and supporting faster decision‐making. You will provide strategic input into protocols, IBs, ICFs, SAPs and DSURs, ensuring safety approaches are scientifically sound, proportionate and patient‐centred.
Your judgement will directly influence how risk is communicated and managed across programmes. You will lead signal detection, agevolazioni–risk assessments and safety governance discussions, acting as a trusted medical voice in high‐impact decisions. By anticipating regulatory expectations, you will help submissions progress with fewer questions and delays.
Working at the centre of development, you will represent Safety on cross‐functional teams, partnering closely with clinical and regulatory colleagues to align safety strategy with programme and corporate goals.
About You
You are a medically

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