The impact of psychedelics on neurodevelopment

Vedi l’offerta su Go Lavoro: golavoro.it/annuncio-lavoro/88swsq

Offer Description

This project investigates the reproductive safety, teratological risks, and therapeutic potential of prenatal psilocybin exposure and its interaction with a model of prenatal THC exposure, the main psychoactive component of Cannabis plant. The main objective is to evaluate whether psilocybin induces long-term alterations in maternal care or offspring neurodevelopment, or whether it can mitigate THC-induced cognitive-social deficits by acting on synaptic plasticity and the modulation of the serotonergic and endocannabinoid systems. Combining in vivo behavioral tests (NOR, OFT, SIT) with high-resolution molecular/epigenetic analyses (NanoString) on the hippocampus and prefrontal cortex,



the study aims to identify sex-specific molecular biomarkers for safety during pregnancy and novel therapeutic targets for treating neurodevelopmental disorders

Where to apply Website

Requirements

Additional Information

Eligibility criteria

Eligible destination country/ies for fellows:

- Italy

Eligibility of fellows: country/ies of residence:
- EUROPE

Eligibility of fellows: nationality/ies:
- EUROPE

Website for additional job details

Work Location(s)

Number of offers available 1 Company/Institute Università degli Studi di Catania Country Italy

Contact City

Catania Website

STATUS: EXPIRED

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Vedi l’offerta su Go Lavoro: golavoro.it/annuncio-lavoro/88swsq