2026_Ir_43_Dibio Selection ForResearch Assignment Entitled "Program - Harnessing Bacprotacs To Disarm Virulence In Gramnegative Bacteria

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Organisation/Company Università degli Studi di Padova Research Field Biological sciences » Biology Researcher Profile Recognised Researcher (R2) Leading Researcher (R4) First Stage Researcher (R1) Established Researcher (R3) Application Deadline 21 Oct *********:00 (UTC) Country Italy Type of Contract To be defined Job Status Not Applicable Is the job funded through the EU Research Framework Programme?
Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure?
No
Offer Description
Expression and purification of the bacterial transcription factors under investigation;
Identification of molecular interactors of the transcription factors under investigation using BioID, co-immunoprecipitation, and reporter assays in bacterial cells;




Structural analysis of protein complexes by X-ray crystallography;
High-throughput screening of ligands targeting proteins of interest using spectroscopic techniques.
Validation and quantification of protein-protein and protein-ligand interactions using molecular biophysics techniques (SPR, ITC, GCI, and FP);
Biochemical assays (enzymatic assays) and microbiological assays (viability assays and RT-PCR) to evaluate the activity of the compounds developed.
Italy
Eligibility of fellows: country/ies of residence:
OTHER
Eligibility of fellows: nationality/ies:
#J-*****-Ljbffr

Vedi l’offerta su Go Lavoro: golavoro.it/annuncio-lavoro/8eqwqv