19 ott - Roma
Italian Ministry of Education, University and Research
Organisation/Company CONSIGLIO NAZIONALE DELLE RICERCHE Research Field Biological sciences » Other Researcher Profile Recognised Researcher (R2) Leading Researcher (R4) First Stage Researcher (R1) Established Researcher (R3) Application Deadline 24 Oct 2026 - 18:00 (UTC) Country Italy Type of Contract To be defined Job Status Not Applicable Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No Offer Description
The MITCAN project aims to develop anti-cancer drugs targeting the GRASP65–GM130 axis, a pathway crucial for the mitotic spindle and chromosomal stability. The work involves characterizing protein-protein interfaces and analyzing the druggability of binding sites using structural molecular modeling, while also handling incomplete experimental data. To identify modulating molecules,
the project will employ virtual screening campaigns (both ligand- and structure-based), drug repurposing studies, pharmacophore modeling, and molecular dynamics simulations. The role entails integrating computational predictions with biological data from the Institute's validation teams and utilizing bioinformatics tools. Additional responsibilities include KPI monitoring, scientific reporting, financial accounting, presenting results to partners and funding bodies, and providing methodological mentoring.
PhD degree in: Medicinal Chemistry, or in chemical or medicinal-chemical disciplines.
Italy
Eligibility of fellows: country/ies of residence:
Italy
Eligibility of fellows: nationality/ies:
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