Study of mitochondrial transfer into thermogenic tissues during aging

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pOrganisation/Company Università degli Studi di Roma Tor Vergata - Dipartimento di Biologia Research Field Biological sciences Researcher Profile Recognised Researcher (R2) Leading Researcher (R4) First Stage Researcher (R1) Established Researcher (R3) Application Deadline 31 Oct 2026 - 23:59 (UTC) Country Italy Type of Contract To be defined Job Status Not Applicable Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No /ph3Offer Description /h3pAging undermines the body's ability to adapt, particularly the function of thermogenic adipose tissue (t-AT), which is essential for metabolism. As we age, the quality of mitochondria declines,



leading to metabolic disorders like insulin resistance and type 2 diabetes When adipocytes are stressed, they release damaged mitochondria that are quickly cleared by macrophages. Thesebr/immune cells transform into "M2" macrophages, which have anti-inflammatory properties. Recent discoveriesbr/indicate that M2 macrophages can transfer their healthy mitochondria to adipocytes, providing bioenergetic support.br/The hypothesis is that with aging, this virtuous cycle is disrupted, accelerating metabolic decline and aggravatingbr/age-related diseases /pulliItaly /li /ulh3Eligibility of fellows: country/ies of residence: /h3ulliOTHER /li /ulh3Eligibility of fellows: nationality/ies: /h3 #J-18808-Ljbffr

Vedi l’offerta su Go Lavoro: golavoro.it/annuncio-lavoro/8mdu8d