Post-doctoral position, Mucosal Immunology and Microbiota Unit
h3Why Humanitas /h3 pChoosing Humanitas means joining an environment where quality of care is built every day through clinical expertise, innovation and teamwork, where everyone contributes to the patient care journey. /p h3Who we are /h3 pHumanitas Research Hospital is a highly specialized research and university hospital, and the first in Italy to be certified as an Academic Hospital by the Joint Commission International. Research is driven daily by over 500 physicians, biologists, physicists, data scientists, and technologists working across hospital wards and 10,000 sqm of high-tech laboratories. Our mission is to transform discoveries into concrete cures, with a strategic focus on five key areas: cancer, immunology, neuroscience, gastrointestinal medicine, and molecular cardiology. /p h3The context /h3 pHumanitas University is looking for a Post-Doctoral Researcher at Humanitas Clinical and Research Hospital in the Mucosal Immunology and Microbiota Unit, directed by Prof. Maria Rescigno. /p pCandidates must hold a Ph.D. in Cell and Molecular Biology, Immunology, Cancer Biology or a related discipline. /p pThe position is linked to the AIRC Investigator Grant (IG 2023) project “Achilles – Analysis of the role of the choroid plexus and the microbiota in brain tumor metastasis formation”. The project investigates how the choroid plexus vascular barrier (PVB) and the microbiota contribute to brain metastasis formation and immune cell recruitment. Using complementary in vivo and molecular approaches, the work will characterize PVB and BBB permeability, immune infiltrates,
microbiota and metabolomic profiles before and during brain metastasis development, and will explore strategies to modulate the PVB for therapeutic purposes /p pThe candidate will contribute to multidisciplinary studies integrating cancer biology, immunology, microbiology and advanced imaging /p h3The person we are looking for: /h3 pExpertise in animal models, immunological assays and molecular biology is required. Preference will be given to candidates with experience in cancer biology or cancer immunology and with experimental skills relevant to the project, including multiparameter flow cytometry, immunofluorescence/confocal microscopy, vascular permeability assays, microbiota profiling and in vivo tumor models. /p pCandidates must have effective skills in oral and written communication, teamwork and problem-solving, and be adaptable to changes in technological and scientific directions. /p pA track record of research experience in recognized laboratories and peer-reviewed scientific publications is required /p h3What we offer /h3 pWorking at Humanitas means contributing to a future where care, wellbeing and professional excellence grow together. For this reason, we offer: /p ul lia wellbeing programme that also includes initiatives supporting physical and psychological health; /li lipractical work-life balance measures /li litraining and development opportunities to foster talent and enhance skills in a dynamic and innovative environment. /li /ul pThis offer is open to candidates in compliance with Legislative Decrees 198/2006, 215/2003 and 216/2003. /p #J-18808-Ljbffr
microbiota and metabolomic profiles before and during brain metastasis development, and will explore strategies to modulate the PVB for therapeutic purposes /p pThe candidate will contribute to multidisciplinary studies integrating cancer biology, immunology, microbiology and advanced imaging /p h3The person we are looking for: /h3 pExpertise in animal models, immunological assays and molecular biology is required. Preference will be given to candidates with experience in cancer biology or cancer immunology and with experimental skills relevant to the project, including multiparameter flow cytometry, immunofluorescence/confocal microscopy, vascular permeability assays, microbiota profiling and in vivo tumor models. /p pCandidates must have effective skills in oral and written communication, teamwork and problem-solving, and be adaptable to changes in technological and scientific directions. /p pA track record of research experience in recognized laboratories and peer-reviewed scientific publications is required /p h3What we offer /h3 pWorking at Humanitas means contributing to a future where care, wellbeing and professional excellence grow together. For this reason, we offer: /p ul lia wellbeing programme that also includes initiatives supporting physical and psychological health; /li lipractical work-life balance measures /li litraining and development opportunities to foster talent and enhance skills in a dynamic and innovative environment. /li /ul pThis offer is open to candidates in compliance with Legislative Decrees 198/2006, 215/2003 and 216/2003. /p #J-18808-Ljbffr