In-Vivo Pulmonary Pharmacology Scientist
Overview
In this role you will join the In Vivo Respiratory Translational Pharmacology team to advance preclinical models for asthma, COPD and other respiratory diseases. You will work cross-functionally to generate pharmacology data, evaluate compounds, and develop disease models that inform clinical candidates and partnerships. You will apply in vivo and ex vivo techniques, including multi-omics, to translate findings into actionable insights. This position offers the chance to impact early drug development within a mission-driven biopharma environment.
Retribuzione / Benefits
pension
private medical insurance
wellbeing programme
flexible benefits programme
relocation support
performance bonuses
Responsabilità
Design and execute in vivo studies to evaluate novel compounds within respiratory programs
Generate comparative pharmacology data to assess efficacy, target engagement, and translational profile
Develop and characterize animal models of pulmonary diseases aligned with project needs
Perform in vivo procedures including administration, sampling, and lung function assessments
Conduct ex vivo analyses (gene expression, biomarkers, molecular/biochemical assays)
Apply multi-omics approaches to characterize disease models and mechanisms of action
Analyze and interpret experimental data and ensure clear result reporting
Present findings at internal meetings and perform literature reviews
Requisiti fondamentali
Ph.D. or equivalent with at least 3 years in biotech/pharma
Proven experience in designing and executing in vivo studies for therapeutic candidates
Experience with respiratory disease models is a plus
Hands-on rodent handling, administration, tissue collection, and harvesting
Animal experimentation certification required
Molecular/biochemical techniques including RNA isolation, qRT-PCR, ELISA/MSD, Western blotting
Data analysis using GraphPad Prism and MS Office
Experience with multi-omics data interpretation is a plus
Ability to plan and execute experiments independently with high lab standards
Strong scientific communication in English, both written and spoken
Collaborative, proactive, and organized mindset
Collaborative
Proactive
Solution-oriented
In vivo study design and execution
Rodent handling and sample collection
Lung function assessment
In this role you will join the In Vivo Respiratory Translational Pharmacology team to advance preclinical models for asthma, COPD and other respiratory diseases. You will work cross-functionally to generate pharmacology data, evaluate compounds, and develop disease models that inform clinical candidates and partnerships. You will apply in vivo and ex vivo techniques, including multi-omics, to translate findings into actionable insights. This position offers the chance to impact early drug development within a mission-driven biopharma environment.
Retribuzione / Benefits
pension
private medical insurance
wellbeing programme
flexible benefits programme
relocation support
performance bonuses
Responsabilità
Design and execute in vivo studies to evaluate novel compounds within respiratory programs
Generate comparative pharmacology data to assess efficacy, target engagement, and translational profile
Develop and characterize animal models of pulmonary diseases aligned with project needs
Perform in vivo procedures including administration, sampling, and lung function assessments
Conduct ex vivo analyses (gene expression, biomarkers, molecular/biochemical assays)
Apply multi-omics approaches to characterize disease models and mechanisms of action
Analyze and interpret experimental data and ensure clear result reporting
Present findings at internal meetings and perform literature reviews
Requisiti fondamentali
Ph.D. or equivalent with at least 3 years in biotech/pharma
Proven experience in designing and executing in vivo studies for therapeutic candidates
Experience with respiratory disease models is a plus
Hands-on rodent handling, administration, tissue collection, and harvesting
Animal experimentation certification required
Molecular/biochemical techniques including RNA isolation, qRT-PCR, ELISA/MSD, Western blotting
Data analysis using GraphPad Prism and MS Office
Experience with multi-omics data interpretation is a plus
Ability to plan and execute experiments independently with high lab standards
Strong scientific communication in English, both written and spoken
Collaborative, proactive, and organized mindset
Collaborative
Proactive
Solution-oriented
In vivo study design and execution
Rodent handling and sample collection
Lung function assessment