In-vivo Pulmonary Pharmacology Scientist
h3In-vivo Pulmonary Pharmacology Scientist /h3 /brpDepartment: Pre-Clinical /p /brpBusiness Area: RD, Pharmacovigilance Regulatory Affairs /p /brpJob Type: Direct Employee /p /brpContract Type: Temporary /p /brpLocation: Parma, IT /p /brbAbout us /b /brpChiesi is an international research-focused biopharmaceutical group with 90 years’ experience, operating in more than 30 countries, with its Headquarter in Parma, Italy. More than 8,000 employees across the group are united by a singular purpose: promoting a healthier world for our people, patients, and the planet. This is what drives us as we research, develop, and market innovative drugs across our main therapeutic areas. Discover more here. /p /brpAt Chiesi we are thinking generations ahead, driving sustainable innovation with purpose. This fosters a culture of reliability, transparency, and ethical behaviour at every level. As a Agevolazioni Corporation and a certified B Corp, we have embedded sustainability in our bylaws and continuously measure our impact. /p /brpDiversity and inclusion are at the heart of who we are. We believe our differences make us stronger. We are a vibrant ecosystem of passionate, talented individuals united by strong values, each bringing unique perspectives that help us to continuously challenge the status quo for the better. /p /brbChiesi Research Development /b /brpOur RD team represents a fundamental asset for the business. It is divided into integrated functional areas focusing on pipeline projects including discovery and preclinical research, global technical development, drug delivery technology, clinical development, regulatory affairs, pharmacovigilance, intellectual property, quality assurance, RD project and portfolio management. Headquartered in the new purpose-built and fully integrated Research and Development Centre in Parma (Italy), the team also has important operations in Paris (France), Chippenham (UK), Cary (US), Stockholm (Sweden), Toronto (Canada) and Shanghai (China). /p /brbWho we are looking for /b /brh3This is what you will do /h3 /brpWe are looking for an In Vivo Pharmacology Scientist to join our In Vivo Respiratory Translational Pharmacology team on a temporary basis. The team develops and applies preclinical animal models to support respiratory drug discovery and development programs, contributing to the identification of new clinical candidates, the characterization of compounds in clinical development, and the evaluation of external opportunities for the treatment of chronic respiratory diseases such as asthma and COPD.
The role requires a background in biological sciences and be technically skilled in in vivo preclinical research as well as molecular techniques. /p /brh3You will be responsible for /h3 /brul /brliSupport the design and execution of in vivo studies to evaluate novel compounds and clinical candidates within respiratory research programs. /li /brliGenerate comparative pharmacology data to assess the efficacy, target engagement, and translational profile of internal compounds versus competitor molecules, supporting compound differentiation and enabling project decision-making. /li /brliContribute to the development and characterization of animal models of pulmonary diseases to address project needs. /li /brliPerform in vivo procedures, including compound administration via multiple routes, sample collection, and lung function assessments. /li /brliConduct ex vivo analyses, including gene expression, biomarker evaluation, and molecular and biochemical assays. /li /brliApply multi-omics approaches to characterize disease models, assess translational relevance, and understand compound mechanisms of action. /li /brliAnalyze and interpret experimental data, ensuring accurate organization and reporting of results. /li /brliPerform literature reviews and communicate findings through presentations at relevant internal meetings. /li /br /ul /brh3You will need to have /h3 /brul /brliPh.D. or equivalent doctoral degree in Pharmacology, Biomedical Sciences, or a related discipline, with at least 3 years of experience in the biotechnology or pharmaceutical industry. /li /brliProven experience in the design and execution of in vivo studies to evaluate novel therapeutic candidates. Experience with respiratory disease models is a plus. /li /brliStrong hands‑on expertise in rodent handling, compound administration, blood/tissue collection, and tissue harvesting. Certification for animal experimentation is required. /li /brliExperience with molecular and biochemical techniques, including RNA isolation, qRT-PCR, ELISA/MSD, Western blotting, and protein analysis from ex vivo tissues. /li /brliExperience in data analysis and interpretation,
including the use of GraphPad Prism and Microsoft Office tools. Experience in the analysis and interpretation of multi‑omics data to support translational research is considered a plus. /li /brliAbility to independently plan and execute experimental activities while maintaining high‑quality laboratory standards. /li /brliGood scientific communication skills, including literature review, data presentation, and written and spoken English. /li /brliCollaborative, proactive, and solution‑oriented mindset, with good planning and organizational skills. /li /br /ul /brh3Location /h3 /brpThe position is based in Paolo Chiesi RD Campus, Parma. /p /brh3Budgeted salary range /h3 /brpThe budgeted salary range approved for this role is between €35.600 and €44.600 . This range reflects the typical compensation expected for candidates with the experience and expertise required for the position. /p /brpFinal offer may vary based on the selected candidate's skills, experience, qualifications, overall profile, and internal equity considerations. /p /brpIn addition, we offer a comprehensive benefits package including , pension, private medical insurance, wellbeing programme, flexible benefits programme and more. /p /brbWhat we offer /b /brpNo matter where your path starts at Chiesi, it leads to inspiring possibilities. Your future is our focus, and we are committed to nurturing your development in our dynamic, friendly environment with access to resources and training every step of the way. /p /brpWe provide top-class benefits, including comprehensive healthcare programs, work-life balance initiatives, and robust relocation support. Our salary package is competitive, comprising a basic salary, performance bonuses, and benefits benchmarked against the external market. Additionally, we offer flexible working arrangements, remote work options, and tax assistance services for foreign colleagues, all designed to help you thrive. /p /brpChiesi is an equal opportunity employer committed to hiring a diverse workforce at all levels of our business. All qualified applicants receive consideration for employment based on attitude and merit, without regard to race, national origin, age, sex, religion, disability, sexual orientation, marital status, military status, gender identity or expression, or any other basis protected by applicable laws. This policy applies to all aspects of employment, including hiring, transfer, promotion, compensation, eligibility for benefits, and termination. /p #J-18808-Ljbffr
The role requires a background in biological sciences and be technically skilled in in vivo preclinical research as well as molecular techniques. /p /brh3You will be responsible for /h3 /brul /brliSupport the design and execution of in vivo studies to evaluate novel compounds and clinical candidates within respiratory research programs. /li /brliGenerate comparative pharmacology data to assess the efficacy, target engagement, and translational profile of internal compounds versus competitor molecules, supporting compound differentiation and enabling project decision-making. /li /brliContribute to the development and characterization of animal models of pulmonary diseases to address project needs. /li /brliPerform in vivo procedures, including compound administration via multiple routes, sample collection, and lung function assessments. /li /brliConduct ex vivo analyses, including gene expression, biomarker evaluation, and molecular and biochemical assays. /li /brliApply multi-omics approaches to characterize disease models, assess translational relevance, and understand compound mechanisms of action. /li /brliAnalyze and interpret experimental data, ensuring accurate organization and reporting of results. /li /brliPerform literature reviews and communicate findings through presentations at relevant internal meetings. /li /br /ul /brh3You will need to have /h3 /brul /brliPh.D. or equivalent doctoral degree in Pharmacology, Biomedical Sciences, or a related discipline, with at least 3 years of experience in the biotechnology or pharmaceutical industry. /li /brliProven experience in the design and execution of in vivo studies to evaluate novel therapeutic candidates. Experience with respiratory disease models is a plus. /li /brliStrong hands‑on expertise in rodent handling, compound administration, blood/tissue collection, and tissue harvesting. Certification for animal experimentation is required. /li /brliExperience with molecular and biochemical techniques, including RNA isolation, qRT-PCR, ELISA/MSD, Western blotting, and protein analysis from ex vivo tissues. /li /brliExperience in data analysis and interpretation,
including the use of GraphPad Prism and Microsoft Office tools. Experience in the analysis and interpretation of multi‑omics data to support translational research is considered a plus. /li /brliAbility to independently plan and execute experimental activities while maintaining high‑quality laboratory standards. /li /brliGood scientific communication skills, including literature review, data presentation, and written and spoken English. /li /brliCollaborative, proactive, and solution‑oriented mindset, with good planning and organizational skills. /li /br /ul /brh3Location /h3 /brpThe position is based in Paolo Chiesi RD Campus, Parma. /p /brh3Budgeted salary range /h3 /brpThe budgeted salary range approved for this role is between €35.600 and €44.600 . This range reflects the typical compensation expected for candidates with the experience and expertise required for the position. /p /brpFinal offer may vary based on the selected candidate's skills, experience, qualifications, overall profile, and internal equity considerations. /p /brpIn addition, we offer a comprehensive benefits package including , pension, private medical insurance, wellbeing programme, flexible benefits programme and more. /p /brbWhat we offer /b /brpNo matter where your path starts at Chiesi, it leads to inspiring possibilities. Your future is our focus, and we are committed to nurturing your development in our dynamic, friendly environment with access to resources and training every step of the way. /p /brpWe provide top-class benefits, including comprehensive healthcare programs, work-life balance initiatives, and robust relocation support. Our salary package is competitive, comprising a basic salary, performance bonuses, and benefits benchmarked against the external market. Additionally, we offer flexible working arrangements, remote work options, and tax assistance services for foreign colleagues, all designed to help you thrive. /p /brpChiesi is an equal opportunity employer committed to hiring a diverse workforce at all levels of our business. All qualified applicants receive consideration for employment based on attitude and merit, without regard to race, national origin, age, sex, religion, disability, sexual orientation, marital status, military status, gender identity or expression, or any other basis protected by applicable laws. This policy applies to all aspects of employment, including hiring, transfer, promotion, compensation, eligibility for benefits, and termination. /p #J-18808-Ljbffr