In-vivo Pulmonary Pharmacology Scientist
Overview
In this role you will join the In Vivo Respiratory Translational Pharmacology team to advance preclinical models for asthma, COPD and other respiratory diseases. You will work cross-functionally to generate pharmacology data, evaluate compounds, and develop disease models that inform clinical candidates and partnerships. You will apply in vivo and ex vivo techniques, including multi-omics, to translate findings into actionable insights. This position offers the chance to impact early drug development within a mission-driven biopharma environment.
Retribuzione / Benefits
- pension
- private medical insurance
- wellbeing programme
- flexible benefits programme
- relocation support
- performance bonuses
Responsabilità
- Design and execute in vivo studies to evaluate novel compounds within respiratory programs
- Generate comparative pharmacology data to assess efficacy, target engagement, and translational profile
- Develop and characterize animal models of pulmonary diseases aligned with project needs
- Perform in vivo procedures including administration, sampling, and lung function assessments
- Conduct ex vivo analyses (gene expression, biomarkers, molecular/biochemical assays)
- Apply multi-omics approaches to characterize disease models and mechanisms of action
- Analyze and interpret experimental data and ensure clear result reporting
- Present findings at internal meetings and perform literature reviews
Requisiti fondamentali
- Ph.D. or equivalent with at least 3 years in biotech/pharma
- Proven experience in designing and executing in vivo studies for therapeutic candidates
- Experience with respiratory disease models is a plus
- Hands-on rodent handling, administration, tissue collection, and harvesting
- Animal experimentation certification required
- Molecular/biochemical techniques including RNA isolation, qRT-PCR, ELISA/MSD, Western blotting
- Data analysis using GraphPad Prism and MS Office
- Experience with multi-omics data interpretation is a plus
- Ability to plan and execute experiments independently with high lab standards
- Strong scientific communication in English, both written and spoken
- Collaborative, proactive, and organized mindset
- Collaborative
- Proactive
- Solution-oriented
- In vivo study design and execution
- Rodent handling and sample collection
- Lung function assessment
In this role you will join the In Vivo Respiratory Translational Pharmacology team to advance preclinical models for asthma, COPD and other respiratory diseases. You will work cross-functionally to generate pharmacology data, evaluate compounds, and develop disease models that inform clinical candidates and partnerships. You will apply in vivo and ex vivo techniques, including multi-omics, to translate findings into actionable insights. This position offers the chance to impact early drug development within a mission-driven biopharma environment.
Retribuzione / Benefits
- pension
- private medical insurance
- wellbeing programme
- flexible benefits programme
- relocation support
- performance bonuses
Responsabilità
- Design and execute in vivo studies to evaluate novel compounds within respiratory programs
- Generate comparative pharmacology data to assess efficacy, target engagement, and translational profile
- Develop and characterize animal models of pulmonary diseases aligned with project needs
- Perform in vivo procedures including administration, sampling, and lung function assessments
- Conduct ex vivo analyses (gene expression, biomarkers, molecular/biochemical assays)
- Apply multi-omics approaches to characterize disease models and mechanisms of action
- Analyze and interpret experimental data and ensure clear result reporting
- Present findings at internal meetings and perform literature reviews
Requisiti fondamentali
- Ph.D. or equivalent with at least 3 years in biotech/pharma
- Proven experience in designing and executing in vivo studies for therapeutic candidates
- Experience with respiratory disease models is a plus
- Hands-on rodent handling, administration, tissue collection, and harvesting
- Animal experimentation certification required
- Molecular/biochemical techniques including RNA isolation, qRT-PCR, ELISA/MSD, Western blotting
- Data analysis using GraphPad Prism and MS Office
- Experience with multi-omics data interpretation is a plus
- Ability to plan and execute experiments independently with high lab standards
- Strong scientific communication in English, both written and spoken
- Collaborative, proactive, and organized mindset
- Collaborative
- Proactive
- Solution-oriented
- In vivo study design and execution
- Rodent handling and sample collection
- Lung function assessment