FRDA Splicing Researcher: Elevate Frataxin Levels

Pubblicato il 09-11-2026 · Italian Ministry of Education, University and Research · Italia

Università di Trento invites researchers to join a FRDA project investigating how reprogramming of FXN pre-mRNA splicing can upregulate frataxin expression, a mitochondrial protein essential for iron-sulfur cluster biogenesis and cellular energy metabolism.

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The program aims to explore the molecular and functional consequences of a novel therapeutic strategy designed to increase endogenous xysqume frataxin expression and to advance understanding of Friedreich ataxia through collaborative research efforts.

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